Unveiling the regioselectivity of rhodium(I)-catalyzed [2 + 2 + 2] cycloaddition reactions for open-cage C₇₀ production

• Cristina Castanyer,
• Anna Pla-Quintana,
• Anna Roglans,
• Albert Artigas and
• Miquel Solà

Beilstein J. Org. Chem. 2024, 20, 272–279, doi:10.3762/bjoc.20.28

• open-cage C60 derivatives have been reported. These open-cage fullerenes can act as molecular containers. Of special interest is the procedure called molecular surgery designed by Murata et al. [22][23][24][25] in which a hole in the fullerene is opened, an atom or small molecule is introduced and then

Supramolecular approaches to mediate chemical reactivity

• Pablo Ballester,
• Qi-Qiang Wang and
• Carmine Gaeta

Beilstein J. Org. Chem. 2022, 18, 1463–1465, doi:10.3762/bjoc.18.152

• constrictions, stabilization of species, and solvent exclusion phenomena occurring in the molecular containers isolated spaces [6]. Consequently, the classical rules of organic reactivity are often violated [6][11]. Taking into account the above considerations, we organized this thematic issue focused on

• and sometimes even unachievable separation and purification procedures. Rui Wang and Yang Yu [16] reported an interesting review in which they summarized various site-selective reactions mediated by molecular containers. They focused their attention on reactions that give different product

Site-selective reactions mediated by molecular containers

• Rui Wang and
• Yang Yu

Beilstein J. Org. Chem. 2022, 18, 309–324, doi:10.3762/bjoc.18.35

• ; microenvironment; molecular containers; noncovalent protective group; site-selectivity; Introduction To run reactions with discriminate control over product selectivity represents one of the huge challenges in organic synthetic chemistry [1], among which, site-selectivity is always crucial to a reaction when

• mimicking the recognition and catalysis behavior of enzymes with designed and synthesized molecular containers such as cyclodextrins, cucurbiturils, calixarenes, and resorcinarenes, chemists try to tackle problems of traditional synthetic chemistry, including increase in reactivity, induction of selectivity

• water solubility, and, on the other hand, these kinds of water-soluble moieties could also be introduced into the structures of other hosts to help them gain some extent of water solubility. In aqueous solution, the molecular containers provide hydrophobic pockets capable of binding a wide range of

Thematic series on supramolecular chemistry

• Christoph A. Schalley

Beilstein J. Org. Chem. 2009, 5, No. 76, doi:10.3762/bjoc.5.76

• , molecular containers, elevators, valves and springs, supramolecular catalysts and many more. Fixing such functional supramolecules in a suitable way, for example on nanoparticles, at interfaces or in membranes can be a way to generate even novel materials with interesting macroscopic effects. This exciting